Dextran Liposome (Dexsome™) Technology
LMI-Vet, LLC is a veterinary biomedical company with exclusive veterinary rights to LifeBlood Medical, Inc.’s. novel, patented, Dexsome technology. The lead product, Dexsome 510, is a veterinary intravenous fluid based on the Dexsome™ technology.
Dexsome TechnologyDexsome ApplicationsThe Dexsome formula was originally developed for cytoprotection and cytopreservation, two critical properties for maintaining organ and tissue viability. Dexsome fluid is comprised of dextran, liposomes, and nutrients. Dextran is a branched glucan molecule, and is used in pharmaceutical intravenous solutions as a volume expander for patients with blood loss and hypovolemia. Liposomes are small spherical vesicles having at least one lipid bilayer, and are used as delivery vehicles for nutrients and pharmaceutical preparations. The combination of these two ingredients produces a unique formula with multiple applications including in IV solutions, cell preservation solutions (biopsies), and other relevant pharmaceutical applications.
LMI-Vet, LLC is developing a range of products from the Dexsome platform. The lead product is Dexsome 510, a veterinary intravenous fluid for veterinary critical care and the general veterinary market. LMI-Vet, LLC estimates that tens of millions of units of veterinary intravenous fluid (IVF) units are used annually in US veterinary practices. Furthermore, recent shortages in veterinary intravenous fluid products have underscored the need for a consistent and reliable source. The Dexsome technology has additional applications in tissue preservation, organ transplants, and as an ideal biopsy preservation solution. hich can be used as a veterinary intravenous fluid, and for other applications including cell preservation (biopsies) and transplant medicine. LMI-Vet, LLC intends on targeting the veterinary pathology and other markets where cell viability is of high importance.
Veterinary intravenous fluids can be used to replace fluid loss, correct electrolyte abnormalities, promote renal diuresis and tissue perfusion. Veterinary intravenous solutions are often used during surgery and/or to replace fluid loss from diarrhea, vomiting, or blood loss. Certain anesthetic agents may decrease blood pressure and tissue perfusion, so veterinary intravenous fluid administration may help maintain tissue and organ perfusion during surgical procedures. There are two primary veterinary intravenous fluid types, being crystalloids or colloids. Crystalloid veterinary intravenous fluids can be hypotonic, normotonic, or hypertonic in nature. Dexsome 510 veterinary intravenous fluid is a crystalloid colloid combination.